Research: Optical Biophysics

Brief summary:

I'm a biomolecular physicist by training, and my research projects were always focused on quantitative optical approaches to investigate biological/biomolecular systems. Optical techniques ranged from label-free spectroscopic approaches to fluorescence-related bioimaging. Biological samples ranged from in vitro models to fixed/living cells, to freely behaving mice.

Research projects:

Neuronal microendoscopy applied to investigate freely-behaving mice's brain activity.
Polarized single-molecule super-resolution fluorescence microscopy applied to human bone cancer cells (actin filament cytoskeletal architecture).
Chitosan antimicrobial interaction with biomembrane models using Langmuir surface thermodynamics and nonlinear vibrational SFG spectroscopy.
Ultrafast (fs) pump-probe spectroscopy applied on conjugated polymers with different bandgap architectures.

Research Teams:

Complex Media Optics Lab (CoMedia), Laboratoire Kastler Brossel (LKB):

École Normale Supérieure (ENS/PSL), Université PSL, Sorbonne Université (SU), and Collège de France (CdF).

Mosaic (Institut Fresnel):

Institut Fresnel (IF/AMU), Aix-Marseille Université (AMU)

Laboratório de Espectroscopia Não-Linear de Interfaces (LENI), Grupo de Polímeros "Bernhard Gross":

Instituto de Física de São Carlos (IFSC/USP), Universidade de São Paulo (USP).

Center for Nano Science and Technology (CNST):

Politenico di Milan (PoliMi/IIT), Istituto Italiano di Tecnologia (IIT)

Keywords along time:

[2022 - now]: Neuronal microendoscopy; light scattering; scattering media; computational imaging; fiber photometry; non-negative matrix factorization; machine learning; animal behavior, ...
[2016-2020]: Fluorescence microscopy; polarized fluorescence microscopy; super-resolution microscopy; single-molecule approaches; single-molecule orientation and wobbling; labeling strategies; actin cytoskeleton; actin binding proteins; actin filament organization; cell morphology, migration, and contractility; cancer cell behavior, ...
[2013-2015]: Antimicrobial biomolecular interactions; cell membrane perturbation mechanisms; lipid interactions; nonlinear SFG vibrational spectroscopy; surface thermodynamics; Langmuir films; chitosan-lipid membrane interactions; biomimetic membrane behavior...
[2010-2012]: Time-resolved excited-state dynamics; ultrafast (fs) pump-probe spectroscopy; photosynthetic models; bionanotechnology; exciton dynamics; bandgap architectures; energy flow behavior, ...

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